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Mayo Clinic Minute: What to do if you have a lump on your arm or leg

Posted on March 25, 2025


Mayo Clinic News Network – A sarcoma is a term for a broad group of cancers that start in the bones or soft tissue, such as muscle, fat, blood vessels, nerves, tendons and joints.

One of the signs of a sarcoma is a lump that can be felt through the skin that may or may not be painful. So if you feel one of these lumps, what should you do?

Watch: The Mayo Clinic Minute

“Many patients will wonder: ‘I have a lump on my arm or my leg. Should I have this evaluated? Who should I see, and when are these symptoms concerning?’” says Dr. Krista Goulding, a Mayo Clinic orthopedic surgeon.

She explains when you should seek medical care, “If you have a lump on your arm or your leg that is growing rapidly or is bigger than the size of a golf ball, this needs rapid attention.”

…article continued below

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The first step in diagnosing a lump is to get advanced imaging, typically starting with a radiograph or X-ray.

“The next step is to get cross-sectional imaging, which means either an MRI or a CT scan,” says Dr. Goulding.

Imaging is then followed by a biopsy to remove a sample of tissue for testing.

Dr. Goulding says:

“This helps our multidisciplinary team make decisions about how to treat these tumors because these tumors can be benign.

…article continued below

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“They can be benign aggressive, meaning that they are not cancerous, but they can cause problems locally.

“And then there can be cancer diagnosis similar to sarcomas and other types of cancers that will need rapid attention.”



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